WHAT WE DO
The major goal of our research is to delineate the neural circuits involved in the manifestation of neuropsychiatric disorders including addiction, maladaptive eating behaviors, and anxiety. To accomplish this, we take a multidisciplinary approach, relying on innovative techniques to selectively perturb and monitor neural activity in genetically specified populations of mammalian neurons.
putting the 'lab' in collaborative
Research in the Stuber lab uses an interdisciplinary approach to study the neural circuit basis of motivated behavior.
We use synergistic methodologies such as confocal and two-photon microscopy, slice electrophysiology, and immunohistochemistry. These techniques are paired with computational strategies to define principles by which genetically defined neuronal networks encode aspects of behavior.
On a larger scale, we aim to determine how neural circuit elements directly regulate motivated behavioral states. To accomplish this, we use in vivo optogenetics during automated measurements of naturalistic behavior.